Neither the standard abortion pill nor progesterone is associated with birth defects.
The American Academy of Obstetricians and Gynecologists stated in its Practice Bulletin Number 225 (reaffirmed 2023): “ No evidence exists to date of a teratogenic effect of mifepristone.” In other words, it does not appear that the abortion pill causes birth defects.
Progesterone, used in the reversal process, has been safely used in pregnancy for over 50 years. Initial studies have found that the birth defect rate in babies born after the APR is less or equal to the rate in the general population.
A 1999 FDA review revealed no increased risk of birth defects in pregnant women taking progesterone. After more than 25 years of progesterone support in pregnancy, the Pope Paul VI Institute has stated, “All of the available evidence strongly supports its safety when used in pregnancy.”